Treatment of the systemic manifestations of Stevens Johnson Syndrome and TEN is currently supportive in many parts of the world. Patients are best cared for in units that specialize in burn management since the most severe complications for this group of patients relate to the absence of the protective function of the skin. The highest mortality rate is seen in patients with the most severe disease. For TEN patients it can approach 27% at centers that specialize in burn care (7). Causes of death include septicemia, respiratory and renal failure. The rate of death in SJS patients is approximately 3%. Survival is excellent in EM-minor.
Stevens–Johnson syndrome (SJS) is a milder form of toxic epidermal necrolysis (TEN).  These conditions were first recognised in 1922.  A classification first published in 1993, that has been adopted as a consensus definition, identifies Stevens–Johnson syndrome, toxic epidermal necrolysis, and SJS/TEN overlap. All three are part of a spectrum of severe cutaneous reactions (SCAR) which affect skin and mucous membranes.  The distinction between SJS, SJS/TEN overlap, and TEN is based on the type of lesions and the amount of the body surface area with blisters and erosions.  It is agreed that the most reliable method to classify EM, SJS, and TEN is based on lesion morphology and extent of epidermal detachment.  Blisters and erosions cover between 3% and 10% of the body in SJS, 11–30% in SJS/TEN overlap, and over 30% in TEN.  The skin pattern most commonly associated with SJS is widespread, often joined or touching (confluent), papuric spots ( macules ) or flat small blisters or large blisters which may also join together.  These occur primarily on the torso . 
Shingles is a reactivation of the varicel-lazoster virus, the same virus that causes chickenpox. If you have had chickenpox, the virus can live on within your nerve cells for years after the sores have gone away. In some people, the varicel-lazoster virus reactivates later in life, travels through the nerve fibers, and emerges in the cornea. If this happens, your eye care professional may prescribe oral anti-viral treatment to reduce the risk of inflammation and scarring in the cornea. Shingles can also cause decreased sensitivity in the cornea.