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The hydrogenation of vegetable oils to produce semisolid products has had unintended consequences. Although the hydrogenation imparts desirable features such as spreadability, texture, "mouth feel," and increased shelf life to naturally liquid vegetable oils, it introduces some serious health problems. These occur when the cis-double bonds in the fatty acid chains are not completely saturated in the hydrogenation process. The catalysts used to effect the addition of hydrogen isomerize the remaining double bonds to their trans configuration. These unnatural trans-fats appear to to be associated with increased heart disease, cancer, diabetes and obesity, as well as immune response and reproductive problems.
In these last few days, I squeezed the remaining amounts of Zanfel from a tube I bought several years ago. It worked to reduce the itching and rash from a local PI infection on my leg. Zanfel did the job for me twice before on local PI infections so I definitely got my money’s worth. However, when I bought it, I, like others here, winched at the price and nearly put it back on the shelf. Later on, when I read through the Zanfel patent online, I was planning to try mixing toothpaste with nonoxynol-9, maybe add a little Tide and sand. But I’m glad to hear that cheaper generic versions of Zanfel are now available. Seems like the various generic versions lack the nonoxynol-9, but it’s pretty easy to add that in, and see if it really makes such a difference. (PS: Thanks vauron for posting your experiment findings.)