Non-steroidale schmerzmittel

While NSAIDs can potentially cause many side effects – some of which may be serious or life-threatening – if prescribed under the right conditions and used as instructed, they can be of great benefit. Your doctor can help you consider the benefits and risks of taking an NSAID to ensure they’re the right treatment option for you.

When you’re taking an NSAID, always use it cautiously and for the shortest time possible. If you need to use these medicines for a long time (for example, to manage the symptoms of arthritis when other therapies don’t offer relief, or when you’re taking low-dose aspirin to prevent a heart attack or stroke), make sure you see your doctor regularly.

The TGA is now working with sponsors of non-aspirin NSAIDs to harmonise the warnings regarding the risk of use in pregnancy, including information about the potential increased risk of miscarriage when the medicine is taken close to the time of conception. The TGA is also working with sponsors to include a warning on the labels of all OTC non-aspirin NSAID products, including those indicated exclusively for period pain, that appropriately addresses this risk. See: Consultation: Non-steroidal anti-inflammatory drugs: proposed additional advisory statement .

  • dose appropriately
  • pick the right drug and formulation?
    • Choose Cox-2 selective.
    • enteric coating (., aspirin) - a little protection, variable absorption
    • buffers (., aspirin) - a little protection, enhanced absorption
  • GI Protection?
    • PGE 2 analog - Misoprostol ® (Good evidence of efficacy)
    • Protectants (sucralfate) - no clear evidence
    • Omeprazole - no clear evidence
    • Cimetidine et al. - do not appear to be particularly effective for prevention.

Non-steroidale schmerzmittel

non-steroidale schmerzmittel

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