--- Stress is often mentioned by CSS patients around the time of their diagnosis, and in a way this seems related to the adrenal glands as well. A patient in another support group reported reading in "The Stress of Life" by Dr. H. Seyle:.... "the adrenal glands are the processors of stress in our bodies. A person's stress resistance will vary with the competence of his adrenals. Continually stressing them, finally depletes them. When we become exhausted by life, on a mental or physical level, our adrenal glands often fail to keep up, and illness ensues".
For example one need no longer ponder on the relatively normal fasting gastrin levels. Indeed if negative feedback control of gastrin release by hydrochloric acid is functioning at this age and this is by no means certain, gastrin level should be lower in IHPS. Their normality would be consistent with a relatively insensitivity of this feedback mechanism at this age (vide infra). Any baby in the pyloric age group who persistently vomits and who is alkalotic is invariably found to have IHPS.  The obvious implication is that babies with IHPS are hypersecretors of acid.