Brain tumors in dogs steroids

Chemotherapy works by inflicting cell damage that is better repaired by normal tissue than tumor tissue. Resistance to chemotherapy might involve survival of tumor tissue that cannot respond to the drug, or the inability of the drug to pass from the bloodstream into the brain. A special barrier exists between the bloodstream and the brain tissue called the blood-brain barrier . Some investigators have tried to improve the effect of chemotherapy by disrupting this barrier or by injecting the drug into the tumor or brain. The goal of another class of drugs is not to kill the tumor cells but, rather, to block further tumor growth. In some cases, growth modifiers (such as breast cancer treatment drug Tamoxifen ) have been used to attempt to stop the growth of tumors resistant to other treatments.

The most common indication of a brain tumor in dogs is seizure , especially seizures that begin for the first time in a dog older than five years of age. Other signs suggestive of a brain tumor include abnormal behavior (., increased aggression), altered consciousness, hypersensitivity to pain or touch in the neck area, vision problems, propulsive circling motions, uncoordinated movement, and a “drunken,” unsteady gait . Non-specific signs such as inappetance, lethargy , and inappropriate urination may also be seen.

Surgery to remove the tumor is typically the first option once a brain tumor has been diagnosed. However, some tumors can't be surgically removed because of their location in the brain. In those cases, chemotherapy and radiation therapy may be options for killing and shrinking the tumor. Sometimes, chemotherapy or radiation is also used after surgery to kill any remaining cancer cells. Tumors that are deep in the brain or in areas that are difficult to reach may be treated with Gamma Knife therapy, which is a form of highly focused radiation therapy.

A biopsy can then be performed to identify the type of brain tumor and whether it is malignant (cancerous). During a biopsy, a small amount of the cancerous tissue is taken and analyzed under a microscope. A biopsy can usually be done during surgery in which all or part of the brain tumor is removed. Tumors buried deep in the brain sometimes cannot be approached safely. In those cases, a biopsy procedure involves using three-dimensional needle technique in which special imaging equipment guides the placement of a needle to allow cells to be drawn into the needle.

  • A complete neurologic examination including the testing of various reflexes provides valuable information on the function of the brain and spinal cord.

  • Cerebrospinal fluid (CSF) analysis is the microscopic examination of CSF retrieved via a spinal tap. The analysis often provides valuable information as to the presence of infection, inflammation, and other abnormalities.

  • X-rays provide information about the bony skull around the brain, and the vertebrae that surround the spinal cord. The brain and spinal cord themselves do not show up well on X-rays, but a special procedure called a myelogram can help highlight various areas of the spine.

  • Computed tomography (CT scan or CAT scan) is a special X-ray technique that provides serial images of the brain and spinal cord using enhanced computer processing.

  • Magnetic resonance imaging (MRI) uses the properties of certain tissues subjected to extremely powerful magnetic fields to generate detailed images of body organs. MRI is a very useful tool in evaluating both the brain and spinal cord.

  • Various electrodiagnostic tests are available to assess different functions of the brain and spinal cord. Such tests include the brain stem auditory evoked response (BAER), which is used to detect deafness; the electroencephalogram (EEG), which may detect abnormalities in brain activity during a seizure disorder; and nerve conduction velocity (NCV), which assesses the function of peripheral nerves.
  • Brain tumors in dogs steroids

    brain tumors in dogs steroids

    A biopsy can then be performed to identify the type of brain tumor and whether it is malignant (cancerous). During a biopsy, a small amount of the cancerous tissue is taken and analyzed under a microscope. A biopsy can usually be done during surgery in which all or part of the brain tumor is removed. Tumors buried deep in the brain sometimes cannot be approached safely. In those cases, a biopsy procedure involves using three-dimensional needle technique in which special imaging equipment guides the placement of a needle to allow cells to be drawn into the needle.

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