Use this medication exactly as directed by your veterinarian. If you do not understand the directions ask the pharmacist or veterinarian to explain them to you. Wash your hands prior to using the eye ointment. Apply a thin film of over the cornea three to four times daily in dogs and cats. The area should be properly cleansed prior to use. Foreign bodies, crusted exudates and debris should be carefully removed. Store . Triple Antibiotic Ophthalmic Ointment at 59° - 77 °F., away from moisture and heat. Keep the tube properly capped.
The overall quality of these trials was low (the Darling & McDonald reviewers agreed that all had at least one area of major weakness), so it is necessary to look at other types of studies to determine the effects of ON prophylaxis. A few studies have treated newborns with prophylaxis and compared their rates of gonorrheal or chlamydial ON to infants in the past who did not receive any prophylaxis. In a large observational study in South Africa, no eye prophylaxis was used for a certain amount of time, and then three hospitals started using silver nitrate and erythromycin. When they compared no prophylaxis to prophylaxis among 30,530 newborns, the number of gonorrheal ON infections dropped from 273 cases per 100,000 births to 34 cases per 100,000 births. However, within the prophylaxis group, there was a failure rate of 20%, in which the eye ointment did not work to prevent ON (Lund et al. 1987).