Animal steroids used for humans

Cyclosporine has been used by veterinary ophthalmologists in the treatment of Pannus for 12 years now. A 1%, % or 2% solution is most often used, and was prepared in an oil base-usually olive, corn or vegetable oil. About five years ago a % cyclosporine ophthalmic ointment called Optimmune (Schering Plough) became available to all veterinary practitioners for the treatment of another eye disorder- keratoconjunctivitis sicca or day eye – where it is quite effective. In pannus cases, however, I find the % ointment produces less success than the 1% solution. With treatment, the active vascularization and granulation tissue often resolves, but the scarring and pigmentation may improve somewhat slowly or not at all.

Combined preparations . A number of trials have been carried out with implants containing two hormones. The combination of an oestrogen with an anabolic steroid, or with progesterone, has met with the greatest responses. Synovex-S has consistently increased gain as well as FCE, with responses averaging about 20% and 17% respectively (20, 21, 22, 34, 35, 36, 37, 42, 43, 44, 45, 46, 47, 48). Hexoestrol + TBA (usually 30 or 45 mg hexoestrol + 300 mg TBA) has resulted in marked increases in gain (24, 25, 26, 29, 49, 50, 51, 52, 53), of the order of 30% and in FCE (25, 49, 50, 51, 53) of the order of 20%. Oestradiol-17β + TBA (20/140 mg) has given similar results (27, 28, 37, 54, 55), as has Zeranol + TBA (36/300 mg), also recently tested (27, 37, 38, 39, 40, 41, 56).

Animal steroids used for humans

animal steroids used for humans

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