Hi Erika, I had AA at 16, then at 46 and again at 48. I had nothing at 16 because doctor said it was mono all grew back in the spots where it fell out in 6 months. At 46 I had steroid shots with success. I had them two years later as well. interestingly enough my aunt had AA at 45. I do know that both times in my 40s when this has happened I felt weak, very run-down and ill, just sick, almost like the mono. About a month after the hair fell out. Is there a connection? Who knows. I have tried to just be accepting of this. It is very hard think if it does happen again I may get counseling just to help me deal with the stress. You may never get it again, there are no guarentees. Best of luck to you and just stay strong.
Subcorneal (under the top layer of the skin) pustular (pus forming) dermatosis (skin problem) is a relatively harmless blistering skin condition. Women develop it more often than men (at a ratio of 4:1), and it usually starts after the age of 40. It may come and go, and can eventually resolve and not require any further (under the top layer of the skin) pustular (pus forming) dermatosis (skin problem) is a rare blistering skin condition. Women get it more often than men (at a ratio of 4:1), and it usually starts after the age of 40. It may come and go, and can eventually resolve and not require any further treatment. Drs Ian Sneddon and Darrell Wilkinson first described the condition in 1956, which is why it is also called Sneddon-Wilkinson-Disease.
A key aspect of hair loss with age is the aging of the hair follicle.  Ordinarily, hair follicle renewal is maintained by the stem cells associated with each follicle. Aging of the hair follicle appears to be primed by a sustained cellular response to the DNA damage that accumulates in renewing stem cells during aging.  This damage response involves the proteolysis of type XVII collagen by neutrophil elastase in response to the DNA damage in the hair follicle stem cells. Proteolysis of collagen leads to elimination of the damaged cells and then to terminal hair follicle miniaturization.